Document Details

Document Type : Thesis 
Document Title :
INFLUENCE OF ORAL CONVOLVULUS HYSTRIX VAHL ROOT BARK ON CARBOHYDRATE, FAT AND PROTEIN METABOLISM
تأثير تناول لحاء جذور نبات الضريع عن طريق الفم على أيض الكربوهيدرات، الدهون و البروتين
 
Subject : Biochemistry 
Document Language : Arabic 
Abstract : “Convolvulus hystrix Vahl” is a plant that has been known to Ancient Egyptians and to Arabs and its root was used traditionally as a purgative. The name of this plant in Arabic language is pronounced as “Dha’Rea’a”. Other local names are “Shabraq”, “Shubrum” or “Shibrim” as being pronounced by some Bedouins in “Sinai” of Egypt and Saudi Arabia up till now. Our attention was directed to the root bark as we observed that largest part of the plant is deeply impeded underground. In the family of Convolvulaceae the thickened roots are storage structure that differs from true tubers. The work plan involved testing experimental animals for the influence of aqueous root bark extract on carbohydrate, fat and protein metabolism as reflected on growth and relevant laboratory metabolic assessment parameters. Proximate analysis showed high percentages of moisture (85%) and total lipids (7.2%) and surprising amounts of elements such barium, strontium, rhodium and tellurium (1.7mg, 3.1mg, 8mg and 9.1mg / gram ash respectively). Random serum glucose value showed a significant decrease in the treated female group (p<0.05). Treated female serum total proteins was found to be increased significantly (p<0.001) while it was found to be decreased in the relevant treated male group (p<0.01), together with a significant decrease in blood urea nitrogen (p<0.05), with a significant increase in the serum creatinine (p<0.05). Concerning serum fat metabolic parameters, it was found that a significant decreased in the serum triglycerides and high density lipoproteins (p<0.01 and p<0.01) respectively. We concluded that the presence of huge amount of polyphenolics such tannins is responsible for the overall results documented as growth retarding and antinutritional factors. The results were motivating and pointed out to the possible opening of vast areas of research in the field of natural products. We recommend a series of biochemical and pharmacological studies concerning different parts of the plant as well. 
Supervisor : Prof. Dr. Alsayed Ameen Rezq 
Thesis Type : Master Thesis 
Publishing Year : 1430 AH
2009 AD 
Co-Supervisor : Dr. Abdulrahman Lubaid Al-Malky 
Added Date : Sunday, December 5, 2010 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
محمد يحيى رفاعيRefai, Mohammed YahyaResearcherMaster 

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